Unexplained DNA melting behavior in a genotyping assay.

tion. We believe that this change will significantly increase the sensitivity for detecting myocardial necrosis (1, 3). In summary, we have shown that the upper reference limit for a healthy population is 0.16 g/L for TnI concentrations measured using the Bayer ACS:Centaur method. The difference between TnI values obtained for serum or heparin-plasma specimens is only just significant at the low concentrations found in a healthy reference population. This difference is not likely to alter the clinical response and so does not justify having a different reference interval related to each specimen type.